49ers vs. Dolphins Week 16 Predictions, Odds and Stats

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Based on our computer projections, the San Francisco 49ers will defeat the Miami Dolphins when the two teams play at Hard Rock Stadium on Sunday, Dec. 22, which begins at 4:25 p.m. ET. For our predictions on the spead, point total, and final score, check out the rest of the article below.

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49ers vs. Dolphins Game Info and TV Channel

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Listen to the game on Fox Sports 940

49ers vs. Dolphins Odds and Betting Info

  • Spread favorite: 49ers (-1.5)
  • Moneyline: 49ers (-123), Dolphins (+103)
  • Total: 44.5 points

49ers vs. Dolphins Prediction

  • Pick ATS: 49ers (-1.5)
  • Pick OU: Under (44.5)

Prediction:

49ers 23 - Dolphins 21

    Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.

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    49ers vs. Dolphins Betting Insights

    • The 49ers have covered five times in 14 games with a spread this season.
    • The Dolphins have covered five times in 14 chances against the spread this season.
    • San Francisco has been favored by 1.5 points or more 12 times this season, and covered the spread in five of those games.
    • Miami has been an underdog by 1.5 points or more six times this season, and covered the spread in two of those matchups.
    • 49ers games have gone over the point total eight out of 14 times this season.
    • The Dolphins and their opponent have combined to go over the point total six out of 14 times this year.

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